Ceftazidime is a broad-spectrum β-lactam antibiotic used as an antimicrobial agent. It is used for treating febrile neutropenia in patients with cancer. It is a third-generation cephalosporin. As a class, cephalosporins have activity against Gram-positive and Gram-negative bacteria. The balance of activity tips toward Gram-positive organisms for earlier generations; later generations of cephalosporins have more Gram-negative coverage. Ceftazidime is one of the few in this class with activity against Pseudomonas.
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Masoud MS, Ali AE, Elasala GS, Kolkaila SA. Synthesis, spectroscopic, biological activity and thermal characterization of ceftazidime with transition metals. Spectrochim Acta A Mol Biomol Spectrosc. 2018 Mar 15;193:458-466. doi: 10.1016/j.saa.2017.12.060. Epub 2017 Dec 24. PubMed PMID: 29289744.
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