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MedKoo Cat#: 461040 | Name: Milenperone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Milenperone is a dopamine receptor antagonist.

Chemical Structure

Milenperone
Milenperone
CAS#59831-64-0

Theoretical Analysis

MedKoo Cat#: 461040

Name: Milenperone

CAS#: 59831-64-0

Chemical Formula: C22H23ClFN3O2

Exact Mass: 415.1463

Molecular Weight: 415.89

Elemental Analysis: C, 63.54; H, 5.57; Cl, 8.52; F, 4.57; N, 10.10; O, 7.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Milenperone; R 34009; R-34009; R34009;
IUPAC/Chemical Name
5-chloro-1-(3-(4-(4-fluorobenzoyl)piperidin-1-yl)propyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
InChi Key
DBESQBZOXMCXPV-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H23ClFN3O2/c23-17-4-7-20-19(14-17)25-22(29)27(20)11-1-10-26-12-8-16(9-13-26)21(28)15-2-5-18(24)6-3-15/h2-7,14,16H,1,8-13H2,(H,25,29)
SMILES Code
O=C(C1CCN(CCCN2C3=CC=C(Cl)C=C3NC2=O)CC1)C4=CC=C(F)C=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 415.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: De Cuyper H, van Praag HM, Verstraeten D. The effect of milenperone on the aggressive behavior of psychogeriatric patients. A double-blind placebo-controlled study. Neuropsychobiology. 1985;13(1-2):1-6. PubMed PMID: 2863777. 2: De Cuyper H, van Praag HM, Verstraeten D. The effect of milenperone on the aggressive behavior of oligophrenic patients. A double-blind placebo-controlled study. Neuropsychobiology. 1985;13(3):101-5. PubMed PMID: 3900796. 3: Gelders YG, Reyntjens AJ, Aerts TJ. Milenperone. A selective drug for the control of behavioral disorders in epileptic and alcoholic patients. Acta Psychiatr Belg. 1984 Mar-Apr;84(2):151-9. PubMed PMID: 6146246. 4: Froimowitz M, Cody V. The incorporation of butyrophenones and related compounds into a pharmacophore for dopamine D2 antagonists. Drug Des Discov. 1997 Aug;15(2):63-81. PubMed PMID: 9342550. 5: Goiny M, Uvnäs-Moberg K, Cekan S. Bromocriptine and apomorphine stimulation of cortisol secretion in conscious dogs; evidence for a stimulatory site located outside the blood brain barrier. Psychopharmacology (Berl). 1986;89(1):108-12. PubMed PMID: 3090584.