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Research areas

Angiogenesis 16

demo333 test3 Bcl-2 VEGFR VDA Syk Src PDGFR JAK HIF FLT3 FGFR FAK EGFR BTK Bcr-Abl

Apoptosis 8

TNF-alpha Survivin PERK p53 Mdm2 IAP c-RET Caspase

Autophagy 2

APC LRRK2

Cell Cycle 9

Akt Wee1 ROCK Rho PLK c-Myc Chk CDK Aurora Kinase

Cytosketetal Signaling 11

ATM/ATR Wnt/beta-catenin PKC PAK Microtubule Kinesin Integrin HSP FAK Dynamin Bcr-Abl

DNA Damage 8

5-alpha Reductase Topoisomerase Telomerase Sirtuin PARP HDAC DNA-PK DNA/RNA Synthesis

Endocrinology & Hormones 8

Aurora Kinase RAAS Opioid Receptor GPR Glucocorticoid Receptor Estrogen/progestogen Receptor Aromatase Androgen Receptor

Epigenetics 12

5-HT Receptor Sirtuin Pim PARP JAK Histone Methyltransferase Histone Demethylase Histone Acetyltransferase HIF HDAC Epigenetic Reader Domain DNA Methyltransferase

GPCR & G Protein 19

EGFR Vasopressin Receptor SGLT S1P Receptor PAFR OX Receptor Opioid Receptor MT Receptor LPA Receptor Histamine Receptor Hedgehog/Smoothened Dopamine Receptor CXCR CGRP Receptor CaSR Cannabinoid Receptor cAMP Adrenergic Receptor Adenosine Receptor

JAK/STAT 4

ERK STAT Pim JAK

MARK 5

ATPase Raf p38 MAPK MEK JNK

Transmembrane Transporters 10

AhR TRPV Sodium Channel Proton Pump Potassium Channel P-gp GABA Receptor CRM1 CFTR Calcium Channel

Metabolism 20

CCR Transferase Retinoid Receptor Procollagen C Proteinase PPAR Phospholipase (e.g. PLA) PDE P450 (e.g. CYP17) MAO IDO Hydroxylase HSP HMG-CoA Reductase Ferroptosis Factor Xa FAAH DHFR Dehydrogenase CETP Carbonic Anhydrase

Microbiology 5

5-HT Receptor Reverse Transcriptase Integrase HIV Protease HCV Protease

Neuronal Signaling 17

HDAC P-gp P2 Receptor OX Receptor Opioid Receptor MT Receptor Histamine Receptor GluR Gamma-secretase GABA Receptor Dopamine Receptor COX CaMK Beta Amyloid BACE Adrenergic Receptor AChR

NF-kB 4

Akt NOD1 NF-κB IκB/IKK

PI3K/AKT/mTOR 9

S6 Kinase Caspase PI3K PDK-1 mTOR GSK-3 DNA-PK ATM/ATR AMPK

Proteases 9

ALK Serine Protease Proteasome MMP HIV Protease HCV Protease Gamma-secretase DPP-4 Cysteine Protease

Protein Tyrosine Kinase 16

Gamma-secretase VEGFR Trk Receptor Tie-2 TAM Receptor PDGFR IGF-1R HER2 FLT3 FGFR Ephrin Receptor EGFR CSF-1R c-RET c-Met c-Kit

Stem Cells / Wnt 8

Bcr-Abl Wnt/beta-catenin TGF-beta/Smad STAT ROCK JAK Hedgehog/Smoothened GSK-3

TGF-beta /Smad 4

DUB TGF-beta ROCK KC

Ubiquitin 5

Proteasome p97 E3 Ligase E2 Conjugating E1 Activating

Lipid reagent 2

Ionizable lipid All lipid reagent

Photodynamic therapy 2

Porphyrin Photodynamic Therapy (PDT)

Test20250626 2

Test0626A Test0626B

Disease areas

MEK Products

AG-490

AG-490

New Featured

MedKoo CAT#: 200121

CAS#: 133550-30-8

50mg / USD 450.00

MedKoo CAT#: 200121

CAS#: 133550-30-8

50mg / USD 450.00

AS703988

AS703988

MedKoo CAT#: 205859

MedKoo CAT#: 205859

Atebimetinib

Atebimetinib

MedKoo CAT#: 128469

CAS#: 2669009-92-9

MedKoo CAT#: 128469

CAS#: 2669009-92-9

Avutometinib

Avutometinib

Featured

MedKoo CAT#: 205788

CAS#: 946128-88-7 (free)

5mg / USD 350.00

MedKoo CAT#: 205788

CAS#: 946128-88-7 (free)

5mg / USD 350.00

AZD-8330

AZD-8330

Featured

MedKoo CAT#: 200313

CAS#: 869357-68-6

10mg / USD 350.00

MedKoo CAT#: 200313

CAS#: 869357-68-6

10mg / USD 350.00

Binimetinib (MEK-162)

Binimetinib (MEK-162)

New Featured

MedKoo CAT#: 205531

CAS#: 606143-89-9

25mg / USD 90.00

MedKoo CAT#: 205531

CAS#: 606143-89-9

25mg / USD 90.00

CCT196969

CCT196969

Featured

MedKoo CAT#: 406645

CAS#: 1163719-56-9

10mg / USD 350.00

MedKoo CAT#: 406645

CAS#: 1163719-56-9

10mg / USD 350.00

CCT241161

CCT241161

Featured

MedKoo CAT#: 406644

CAS#: 1163719-91-2

1mg / USD 350.00

MedKoo CAT#: 406644

CAS#: 1163719-91-2

1mg / USD 350.00

CI-1040

CI-1040

Featured

MedKoo CAT#: 200771

CAS#: 212631-79-3

10mg / USD 350.00

MedKoo CAT#: 200771

CAS#: 212631-79-3

10mg / USD 350.00

CInQ-03

CInQ-03

MedKoo CAT#: 406199

CAS#: 500272-80-0

MedKoo CAT#: 406199

CAS#: 500272-80-0

Cobimetinib free base

Cobimetinib free base

New Featured

MedKoo CAT#: 203185

CAS#: 934660-93-2 (free base)

5mg / USD 90.00

MedKoo CAT#: 203185

CAS#: 934660-93-2 (free base)

5mg / USD 90.00

Debio-0932

Debio-0932

New Featured

MedKoo CAT#: 205737

CAS#: 1061318-81-7

5mg / USD 120.00

MedKoo CAT#: 205737

CAS#: 1061318-81-7

5mg / USD 120.00

DK2403

DK2403

MedKoo CAT#: 130521

CAS#: 2902651-64-1

MedKoo CAT#: 130521

CAS#: 2902651-64-1

E6201

E6201

MedKoo CAT#: 201071

CAS#: 603987-35-5

MedKoo CAT#: 201071

CAS#: 603987-35-5

Encorafenib

Encorafenib

New Featured

MedKoo CAT#: 205852

CAS#: 1269440-17-6

10mg / USD 150.00

MedKoo CAT#: 205852

CAS#: 1269440-17-6

10mg / USD 150.00

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